Zotsatira zake ndi zabwino kwa opanga mayeso a antigen, omwe awona kuchepa kwa kufunikira pambuyo poyambitsa katemera.
Kafukufuku wochepa wothandizidwa ndi National Institutes of Health (NIS) adapeza kuti Covid-19 lateral flow test (LFT) ndiyothandiza ngati mayeso a polymerase chain reaction (PCR) pozindikira matenda a SARS-CoV-2.Imachitidwa masiku atatu aliwonse One screening.
Mayeso a PCR amatengedwa ngati muyezo wagolide wodziwira matenda a Covid-19, koma kugwiritsa ntchito kwawo ngati zida zowunikira kumakhala kochepa chifukwa amayenera kukonzedwa mu labotale ndipo zotsatira zake zitha kutenga masiku angapo kuti zifikire odwala.
Mosiyana ndi izi, LFT ikhoza kupereka zotsatira m'mphindi zochepa za 15, ndipo ogwiritsa ntchito safunikiranso kuchoka panyumba.
Ofufuza omwe ali ndi NIH Diagnostic Rapid Acceleration Programme adanenanso za zotsatira za anthu 43 omwe ali ndi Covid-19.Ophunzirawo anali ochokera ku University of Illinois ku Urbana-Champaign (UIUC) SHIELD Illinois Covid-19 screening program.Adadziyezetsa okha kapena adalumikizana kwambiri ndi anthu omwe adapezeka ndi kachilomboka.
Otenga nawo mbali adaloledwa patangotha masiku ochepa atapezeka ndi kachilomboka, ndipo zotsatira zake zinali zopanda pake mkati mwa masiku 7 asanalembetse.
Onse anapereka zitsanzo za malovu ndi mitundu iwiri ya swabs ya m'mphuno kwa masiku 14 otsatizana, omwe adakonzedwa ndi PCR, LFT, ndi chikhalidwe cha kachilombo ka HIV.
Kulima ma virus ndi njira yolimbikitsira kwambiri komanso yotsika mtengo yomwe siigwiritsidwa ntchito poyezetsa Covid-19, koma imathandizira kudziwa mtundu wa kachilomboka kuchokera ku zitsanzo.Izi zitha kuthandiza ofufuza kuyerekeza kuyambika ndi nthawi ya kufalikira kwa Covid-19.
Christopher Brooke, Pulofesa wa Molecular and Cell Biology ku UIUC, anati: “Mayeso ambiri amapeza chibadwa chokhudzana ndi kachilomboka, koma izi sizikutanthauza kuti pali kachilombo kamoyo.Njira yokhayo yodziwira ngati pali kachilombo koyambitsa matenda, kamene kamakhala ndi kachilombo ndikutsimikiza za Infectivity kapena chikhalidwe. ”
Kenako, ofufuzawo adayerekeza njira zitatu zodziwira kachilombo ka Covid-19- PCR kuzindikira malovu, kuzindikira kwa PCR kwa zitsanzo za m'mphuno, komanso kuzindikira mwachangu kwa Covid-19 antigen kwa zitsanzo za m'mphuno.
Zotsatira zachitsanzo za malovu zimachitidwa ndi mayeso ovomerezeka a PCR otengera malovu opangidwa ndi UIUC, otchedwa covidSHIELD, omwe amatha kutulutsa zotsatira pakatha pafupifupi maola 12.Kuyesa kosiyana kwa PCR pogwiritsa ntchito chipangizo cha Abbott Alinity kumagwiritsidwa ntchito kupeza zotsatira kuchokera ku mphuno.
Kuzindikira mwachangu kwa antigen kunachitika pogwiritsa ntchito Quidel Sofia SARS antigen fluorescence immunoassay, LFT, yomwe ili yovomerezeka kuti isamalidwe mwachangu ndipo imatha kutulutsa zotsatira pakatha mphindi 15.
Kenako, ofufuzawo adawerengera kukhudzika kwa njira iliyonse pozindikira SARS-CoV-2 ndikuyezanso kupezeka kwa kachilombo kamoyo mkati mwa milungu iwiri kuchokera pomwe adayamba kutenga kachilomboka.
Adapeza kuti kuyezetsa kwa PCR kumakhala kovutirapo kuposa kuyesa kwachangu kwa Covid-19 antigen poyesa kachilomboka nthawi ya kachilomboka isanachitike, koma adanenanso kuti zotsatira za PCR zitha kutenga masiku angapo kuti zibwezedwe kwa munthu yemwe akuyesedwa.
Ofufuzawo adawerengera kukhudzika kwa mayeso kutengera kuchuluka kwa mayeso ndipo adapeza kuti kukhudzika kozindikira matenda ndikwambiri kuposa 98% mayesowo akamayesedwa masiku atatu aliwonse, kaya ndi mayeso othamanga a Covid-19 antigen kapena mayeso a PCR.
Pamene amawunika pafupipafupi kudziwika kamodzi pa sabata, kukhudzika kwa PCR kuzindikira kwa mphuno ndi malovu kudali kwakukulu, pafupifupi 98%, koma kukhudzika kwa antigen kuzindikira kunatsika mpaka 80%.
Zotsatira zikuwonetsa kuti kugwiritsa ntchito kuyezetsa kwachangu kwa Covid-19 antigen osachepera kawiri pa sabata pakuyezetsa Covid-19 kumakhala ndi magwiridwe antchito ofanana ndi mayeso a PCR ndipo kumakulitsa mwayi wozindikira munthu yemwe ali ndi kachilomboka atangoyamba kumene matendawa.
Zotsatira izi zilandilidwa ndi opanga mayeso othamanga a antigen, omwe posachedwapa adanenanso kuti kufunikira kwa kuyezetsa Covid-19 kwatsika chifukwa choyambitsa katemera.
Zogulitsa zonse za BD ndi Quidel pazopeza zaposachedwa zinali zotsika kuposa zomwe akatswiri amayembekezera, ndipo kufunikira kwa kuyezetsa kwa Covid-19 kutsika kwambiri, Abbott adatsitsa malingaliro ake a 2021.
Pa nthawi ya mliri, asing'anga amatsutsana pakugwira ntchito kwa LFT, makamaka pamapulogalamu akuluakulu oyesa, chifukwa nthawi zambiri samachita bwino pozindikira matenda asymptomatic.
Kafukufuku wofalitsidwa ndi US Centers for Disease Control and Prevention mu Januwale adawonetsa kuti mayeso ofulumira a Abbott BinaxNOW atha kuphonya pafupifupi magawo awiri mwa atatu a matenda asymptomatic.
Nthawi yomweyo, mayeso a Innova omwe amagwiritsidwa ntchito ku UK adawonetsa kuti kukhudzidwa kwa odwala omwe ali ndi Covid-19 kunali 58% yokha, pomwe zowerengeka zochepa zoyendetsa zidawonetsa kuti kumva kwa asymptomatic kunali 40% yokha.
Nthawi yotumiza: Jul-22-2021