Patha chaka chopitilira coronavirus yatsopano idawonekera m'miyoyo yathu, koma pali mafunso ambiri omwe madotolo ndi asayansi sangathe kuyankha.
Limodzi mwamafunso ofunikira kwambiri ndiloti mudzakhala otetezedwa nthawi yayitali bwanji mukachira ku matendawo.
Ili ndi funso lomwe aliyense amadabwa nalo, kuyambira asayansi mpaka pafupifupi padziko lonse lapansi.Nthawi yomweyo, omwe adalandira katemera woyamba amafunanso kudziwa ngati alibe kachilomboka.
Kuyeza kwa ma antibodies kungathandize kuthetsa ena mwamavutowa, koma mwatsoka, sikumapereka chidziŵitso chonse cha kuchuluka kwa chitetezo chamthupi.
Komabe, atha kuthandizabe, ndipo madotolo a labotale, akatswiri ammunologists ndi ma virus akufotokozera mwatsatanetsatane zomwe muyenera kudziwa.
Pali mitundu iwiri ikuluikulu: yoyezetsa yomwe imayesa kupezeka kwa ma antibodies, ndi mayeso ena omwe amawunika momwe ma antibodieswa amachitira motsutsana ndi kachilomboka.
Kwa omaliza, otchedwa kuyesa kwa neutralization, seramu imalumikizidwa ndi gawo la coronavirus mu labotale kuti awone momwe ma antibody amachitira komanso momwe kachilomboka kamakanira.
Ngakhale mayesowa sapereka chitsimikizo chotsimikizika, nkoyenera kunena kuti "kuyesa kwabwino kosagwirizana nthawi zonse kumatanthauza kuti mumatetezedwa," atero a Thomas Lorentz ochokera ku gulu la madokotala aku labotale yaku Germany.
Katswiri wa chitetezo chamthupi Carsten Watzl akunena kuti kuyesa kwa neutralization ndikolondola.Koma kafukufuku akuwonetsa kuti pali kulumikizana pakati pa kuchuluka kwa ma antibodies ndi kuchuluka kwa ma antibodies omwe amachepetsa."M'mawu ena, ngati ndili ndi ma antibodies ambiri m'magazi anga, ndiye kuti ma antibodies onsewa sangathe kulunjika mbali yolondola ya kachilomboka," adatero.
Izi zikutanthauza kuti ngakhale mayeso osavuta a antibody atha kukupatsani chitetezo china, ngakhale digiri yomwe angakuuzeni ili ndi malire.
"Palibe amene angakuuzeni momwe chitetezo chenicheni chilili," adatero Watzl."Mutha kugwiritsa ntchito ma virus ena, koma sitinafike pamlingo wa coronavirus."Chifukwa chake, ngakhale ma antibodies anu ali okwera, pakadali kusatsimikizika.
Lorentz adati ngakhale izi zimasiyanasiyana malinga ndi mayiko, m'madera ambiri ku Europe, kuyesa kwa antibody komwe madokotala amatolera magazi ndikutumiza ku labotale kuti akaunike kungawononge ndalama zokwana 18 Euros ($22), pomwe kuyesa kwa neutralization kuli Pakati pa 50 ndi 90 Euros (60). -110 USD).
Palinso mayeso ena omwe ali oyenera kugwiritsidwa ntchito kunyumba.Mutha kutenga magazi m'manja mwanu ndikuwatumiza ku labotale kuti akawunike kapena kuwaponya m'bokosi loyesera - ofanana ndi mayeso othamanga a antigen a matenda oopsa a coronavirus.
Komabe, Lorenz amalangiza kuti musadziyese nokha.Zida zoyesera, ndiyeno mumatumiza magazi anu, omwe amawononga mpaka $70.
Zitatu ndizosangalatsa kwambiri.Kuyankha mwachangu kwa thupi la munthu ku ma virus ndi ma antibodies a IgA ndi IgM.Amapanga mwachangu, koma milingo yawo m'magazi pambuyo pa matenda imatsikanso mwachangu kuposa gulu lachitatu la ma antibodies.
Awa ndi ma antibodies a IgG, opangidwa ndi "maselo okumbukira", ena omwe amatha kukhala m'thupi kwa nthawi yayitali ndikukumbukira kuti kachilombo ka Sars-CoV-2 ndiye mdani.
"Omwe adakali ndi ma cell okumbukira amatha kupanga ma antibodies ambiri atsopano pakafunika," adatero Watzl.
Thupi silipanga ma antibodies a IgG mpaka masiku angapo mutatenga kachilomboka.Chifukwa chake, mukayesa antibody yamtunduwu monga mwanthawi zonse, akatswiri amati muyenera kudikirira patadutsa milungu iwiri mutadwala.
Nthawi yomweyo, mwachitsanzo, ngati mayeso akufuna kudziwa ngati ma antibodies a IgM alipo, akhoza kukhala opanda pake pakangotha milungu ingapo mutatenga kachilomboka.
"Panthawi ya mliri wa coronavirus, kuyesa ma antibodies a IgA ndi IgM sikunachite bwino," adatero Lorenz.
Izi sizikutanthauza kuti simukutetezedwa ndi kachilomboka.Marcus Planning, dokotala wa ku Germany pachipatala cha University of Freiburg, anati: “Taona anthu amene ali ndi matenda ocheperako pang’ono ndipo ma antibodies awo atsika mofulumira.”
Izi zikutanthawuzanso kuti kuyesa kwawo kwa antibody posachedwapa kudzakhala kolakwika-koma chifukwa cha ma T cell, amathabe kupeza chitetezo china, chomwe ndi njira ina yomwe thupi lathu limalimbana ndi matenda.
Sadzalumphira pa kachilomboka kuti asawatseke pama cell anu, koma adzawononga ma cell omwe amawukiridwa ndi kachilomboka, kuwapanga kukhala gawo lofunikira pakuyankha kwanu kwa chitetezo chamthupi.
Anati izi zikhoza kukhala chifukwa chakuti mutatenga kachilomboka, mumakhala ndi chitetezo chokwanira cha T cell, chomwe chimatsimikizira kuti mumadwala pang'ono kapena mulibe, ngakhale muli ndi chitetezo chochepa kapena mulibe.
Mwachidziwitso, aliyense amene akufuna kuyesa maselo a T akhoza kuyesa magazi malinga ndi malo awo, chifukwa madokotala osiyanasiyana a labotale amapereka mayesero a T cell.
Nkhani ya ufulu ndi ufulu imatengeranso komwe muli.Pali malo angapo omwe amapatsa aliyense yemwe watenga kachilombo ka COVID-19 m'miyezi isanu ndi umodzi yapitayo ufulu wofanana ndi wolandira katemera.Komabe, kuyesa kwa antibody sikokwanira.
"Pakadali pano, njira yokhayo yotsimikizira nthawi ya matenda ndi kuyezetsa kwa PCR," adatero Watzl.Izi zikutanthauza kuti mayeso ayenera kuchitidwa kwa masiku osachepera 28 osapitirira miyezi isanu ndi umodzi.
Watzl adati izi ndizofunikira makamaka kwa anthu omwe ali ndi chitetezo chamthupi kapena omwe amamwa ma immunosuppressive agents."Ndi iwo, mutha kuwona kuchuluka kwa ma antibody atalandira katemera wachiwiri."Kwa wina aliyense, kaya katemera kapena kuchira, Watzl amakhulupirira kuti kufunikirako ndi "kochepa."
Lorenz adati aliyense amene akufuna kuyesa chitetezo chamthupi ku coronavirus ayenera kusankha mayeso osalowerera ndale.
Anatinso sangaganize nthawi ina iliyonse kuyesa kosavuta kwa antibody kungamveke, pokhapokha mutangofuna kudziwa ngati muli ndi kachilomboka.
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6698: 351 njira
Nthawi yotumiza: Jun-23-2021