Akatswiri a Epidemiologists akuyerekeza kuti anthu opitilira 160 miliyoni padziko lonse achira ku COVID-19

Akatswiri a Epidemiologists akuyerekeza kuti anthu opitilira 160 miliyoni padziko lonse achira ku COVID-19.Omwe achira amakhala ndi kachulukidwe kowopsa ka matenda, matenda kapena kufa.Kutetezedwa kwa matenda am'mbuyomu kumeneku kumateteza anthu ambiri omwe pakadali pano alibe katemera.
Kumayambiriro kwa mwezi uno, World Health Organisation idatulutsa zosintha zasayansi zonena kuti anthu ambiri omwe achira ku COVID-19 adzakhala ndi chitetezo champhamvu choteteza chitetezo.Chofunika kwambiri, adatsimikiza kuti mkati mwa milungu inayi atatenga kachilombo, 90% mpaka 99% ya anthu omwe achira ku COVID-19 apanga ma antibodies odziwika.Kuphatikiza apo, adatsimikiza - poganizira nthawi yochepa yowonera milandu - chitetezo chamthupi chimakhalabe champhamvu kwa miyezi 6 mpaka 8 pambuyo pa matenda.
Zosinthazi zikufanana ndi lipoti la NIH mu Januware 2021: Anthu opitilira 95% omwe achira ku COVID-19 ali ndi chitetezo chamthupi chomwe chimakhala ndi kukumbukira kosatha kwa kachilomboka kwa miyezi 8 atadwala.Bungwe la National Institutes of Health linanenanso kuti zomwe zapezedwazi "zimapereka chiyembekezo" kuti anthu omwe ali ndi katemera adzakhala ndi chitetezo chokwanira chofanana.
Nanga ndichifukwa chiyani timasamala kwambiri za chitetezo chamthupi chomwe chimapangidwa ndi katemera - ndi cholinga chokwaniritsa chitetezo cha ziweto, cheke paulendo, zochitika zapagulu kapena zachinsinsi, kapena kugwiritsa ntchito masks - kwinaku tikunyalanyaza chitetezo chachilengedwe?Kodi iwo omwe ali ndi chitetezo chamthupi sakuyenera kuyambiranso ntchito zanthawi zonse?
Asayansi ambiri apeza kuti chiopsezo chotenganso kachilomboka chachepetsedwa, ndipo kugonekedwa m'chipatala ndi kufa chifukwa chotenganso kachilomboka ndizochepa kwambiri.M'maphunziro asanu ndi limodzi okhudza anthu pafupifupi 1 miliyoni omwe adachitika ndi United States, United Kingdom, Denmark, Austria, Qatar, ndi United States Marine Corps, kutsika kwa kufalikira kwa COVID-19 kudachokera pa 82% mpaka 95%.Kafukufuku waku Austrian adapezanso kuti kuchuluka kwa kuyambiranso kwa COVID-19 kudapangitsa kuti anthu 5 mwa 14,840 (0.03%) agoneke m'chipatala, ndipo m'modzi mwa anthu 14,840 (0.01%) adamwalira.
Kuphatikiza apo, zidziwitso zaposachedwa zaku US zomwe zidatulutsidwa pambuyo pa chilengezo cha NIH mu Januwale zidapeza kuti ma antibodies oteteza amatha mpaka miyezi 10 atadwala.
Pamene opanga mfundo za umoyo wa anthu amachepetsa chitetezo chawo ku katemera, zokambirana zanyalanyaza kwambiri zovuta za chitetezo cha mthupi cha munthu.Pali malipoti angapo olimbikitsa ofufuza omwe akuwonetsa kuti maselo amwazi m'thupi lathu, omwe amatchedwa "maselo a B ndi T cell", amathandizira kuti chitetezo cham' cell chikhale cholimba pambuyo pa COVID-19.Ngati chitetezo cha SARS-CoV-2 chikufanana ndi matenda ena akuluakulu a coronavirus, monga chitetezo cha SARS-CoV-1, ndiye kuti chitetezochi chitha kukhala zaka 17.Komabe, mayeso omwe amayesa chitetezo cham'manja ndi ovuta komanso okwera mtengo, zomwe zimawapangitsa kukhala ovuta kuwapeza ndikulepheretsa kugwiritsidwa ntchito kwawo pazachipatala kapena kafukufuku waumoyo wa anthu.
A FDA avomereza kuyesa kwa ma antibody ambiri.Monga mayeso aliwonse, amafunikira ndalama ndi nthawi kuti apeze zotsatira, ndipo kachitidwe ka mayeso aliwonse amakhala ndi kusiyana kofunikira pa zomwe antibody yodziwika bwino imayimira.Kusiyana kwakukulu ndikuti kuyezetsa kwina kumangowona ma antibodies omwe amapezeka pambuyo pa matenda achilengedwe, ma antibodies "N", pomwe ena sangathe kusiyanitsa pakati pa ma antibodies achilengedwe kapena opangidwa ndi katemera, ma "S" achitetezo.Madokotala ndi odwala akuyenera kulabadira izi ndikufunsa kuti ndi ma antibodies ati omwe mayesowo amayesa.
Sabata yatha, pa Meyi 19, a FDA adatulutsa kalata yoteteza anthu kuti ngakhale kuyesa kwa SARS-CoV-2 antibody kumachita gawo lofunikira pakuzindikiritsa anthu omwe ali ndi kachilombo ka SARS-CoV-2 ndipo atha kukhala ndi chitetezo chokwanira. Kuyankha, kuyesa kwa antibody sikuyenera kugwiritsidwa ntchito kudziwa chitetezo kapena chitetezo ku COVID-19.Sichoncho?
Ngakhale kuli kofunika kulabadira uthengawo, n’kosokoneza.A FDA sanapereke zambiri mu chenjezoli ndipo adasiya omwe adachenjezedwa osatsimikiza chifukwa chake kuyezetsa kwa antibody sikuyenera kugwiritsidwa ntchito kudziwa chitetezo kapena chitetezo ku COVID-19.Mawu a FDA adapitiliza kunena kuti kuyesa kwa antibody kuyenera kugwiritsidwa ntchito ndi omwe ali ndi chidziwitso pakuyesa kwa antibody.palibe thandizo.
Monga momwe zimakhalira ndi momwe boma la federal likuyankhira ku COVID-19, ndemanga za FDA zimatsalira kumbuyo kwa sayansi.Popeza 90% mpaka 99% ya anthu omwe achira ku COVID-19 apanga ma antibodies osadziwika, madotolo atha kugwiritsa ntchito mayeso oyenera kudziwitsa anthu za chiwopsezo chawo.Titha kuuza odwala kuti anthu omwe achira ku COVID-19 ali ndi chitetezo champhamvu choteteza, chomwe chingawateteze ku matenda, matenda, kugona m'chipatala, ndi imfa.M'malo mwake, chitetezo ichi ndi chofanana kapena chabwino kuposa chitetezo chopangidwa ndi katemera.Mwachidule, anthu omwe achira matenda am'mbuyomu kapena omwe ali ndi ma antibodies odziwika ayenera kuonedwa ngati otetezedwa, ofanana ndi omwe adalandira katemera.
Poyang'ana zam'tsogolo, opanga mfundo akuyenera kuphatikiza chitetezo chachilengedwe monga momwe zimatsimikizidwira ndi mayeso olondola komanso odalirika a antibody kapena zolemba zamatenda am'mbuyomu (omwe anali ndi PCR kapena mayeso a antigen) ngati umboni womwewo wa chitetezo chamthupi monga katemera.Chitetezo ichi chiyenera kukhala ndi chikhalidwe chofanana ndi chitetezo chopangidwa ndi katemera.Ndondomeko yotereyi idzachepetsa kwambiri nkhawa ndikuwonjezera mwayi woyenda, zochitika, maulendo a mabanja, ndi zina zotero. Ndondomeko yosinthidwa idzalola iwo omwe achira kukondwerera kuchira kwawo powauza za chitetezo chawo, kuwalola kutaya masks mosamala, kusonyeza nkhope zawo. ndi kulowa usilikali katemera.
Jeffrey Klausner, MD, MPH, ndi pulofesa wa zachipatala ku Keck School of Medicine ku yunivesite ya Southern California, Los Angeles, ndi dokotala wakale wa Centers for Disease Control and Prevention.Noah Kojima, MD, ndi dotolo wokhala m'chipatala chamkati ku University of California, Los Angeles.
Klausner ndi mkulu wa zachipatala ku kampani yoyesera ya Curative ndipo adawulula ndalama za Danaher, Roche, Cepheid, Abbott ndi Phase Scientific.M'mbuyomu adalandira ndalama kuchokera kwa NIH, CDC, ndi opanga mayeso achinsinsi ndi makampani opanga mankhwala kuti afufuze njira zatsopano zodziwira ndi kuchiza matenda opatsirana.
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