Timagwiritsa ntchito makeke kuti tikulitse zomwe mumakumana nazo.Mukapitiliza kuyang'ana webusayiti iyi, mukuvomera kugwiritsa ntchito makeke.Zambiri.
Zotsatira zenizeni zimadalira kukhulupirika kwa pepala loyesa mkodzo.Mosasamala kanthu za mtunduwo, kusamalidwa kosayenera kwa mizere kungayambitse zotsatira zolakwika, zomwe zingayambitse matenda osadziwika bwino.Botolo la peel lomangidwa molakwika kapena lopangidwanso limawonetsa zomwe zili m'malo achinyezi mumpweya wamkati, zomwe zingakhudze kukhulupirika kwa peel, kupangitsa kuwonongeka kwa reagent, ndipo pamapeto pake kumabweretsa zotsatira zolakwika.
Crolla et al.1 adachita kafukufuku momwe mizere yoyesera idawululidwa ndi mpweya wamkati, ndipo zida ndi zingwe za opanga atatu zidafaniziridwa.Chotengeracho chiyenera kusindikizidwa molingana ndi malingaliro a wopanga pambuyo pa ntchito, apo ayi zingayambitse mpweya wamkati.Nkhaniyi ikupereka lipoti zotsatira za kafukufukuyu, kufananiza mzere woyesa mkodzo wa MULTISTIX® 10SG ndi Nokia CLINTEK Status®+ analyzer ndi zinthu zochokera kwa opanga ena awiri.
Zingwe za Siemens MULTISTIX® zotulutsa mkodzo (Chithunzi 1) zili ndi bandi yatsopano yozindikiritsa (ID).Zikaphatikizidwa ndi CLINITEK Status range⒜ chemistry analyzer yomwe yawonetsedwa pachithunzichi, macheke angapo odziwikiratu (Auto-Check) 2.
Chithunzi 2. CLINTEK Status series analyzers amagwiritsa ntchito algorithm kuti azindikire zingwe zowonongeka zowonongeka ndi chinyezi kuti zitsimikizire zotsatira zabwino.
Krolla ndi al.Kafukufukuyu adawunikira zotsatira zomwe zimapangidwa ndi kuphatikiza kwa mizere yoyesera ndi zowunikira kuchokera kwa opanga atatu:
Kwa wopanga aliyense, magawo awiri a reagents amakonzedwa.Gulu loyamba la mabotolo linatsegulidwa ndikuwululidwa ndi mpweya wamkati (22oC mpaka 26oC) ndi chinyezi chamkati (26% mpaka 56%) kwa masiku oposa 40.Izi zachitika kuti yesezera kukhudzana kuti reagent Mzere akhoza poyera pamene woyendetsa si bwino kutseka reagent Mzere chidebe (anzanu Mzere).Mu gulu lachiwiri, botolo linasungidwa losindikizidwa mpaka chitsanzo cha mkodzo chiyesedwe (palibe choponderetsa).
Pafupifupi zitsanzo za mkodzo wa odwala 200 zinayesedwa m'mitundu yonse itatu.Zolakwa kapena voliyumu yosakwanira pakuyesa zipangitsa kuti chitsanzocho chikhale chosiyana pang'ono.Chiwerengero chonse cha zitsanzo zoyesedwa ndi wopanga zafotokozedwa mwatsatanetsatane mu Gulu 1. Mayeso a regent strip adachitidwa pazowunikira zotsatirazi pogwiritsa ntchito zitsanzo za odwala:
Kuyesa kwa mkodzo kumatsirizidwa mkati mwa miyezi itatu.Pamagulu aliwonse, opsinjika ndi osapsinjika, zitsanzo zoyeserera zimabwerezedwa pamakina onse a zida.Pa kuphatikiza kulikonse kwa mizere ndi analyzer, yendetsani zitsanzo izi mosalekeza.
Malo opangira odwala kunja omwe ali m'tawuni ndi malo opangira kafukufuku.Mayeso ambiri amachitidwa ndi othandizira azachipatala ndi ogwira ntchito ya unamwino, ndipo mayeso apakatikati amachitidwa ndi ogwira ntchito mu labotale ophunzitsidwa bwino (ASCP).
Kuphatikizika kwa ogwira ntchito kumeneku kumatengera zomwe zayesedwa m'malo opangira chithandizo.Asanasonkhanitse deta, onse ogwira ntchito adaphunzitsidwa ndipo mphamvu zawo zidawunikidwa pa osanthula onse atatu.
Mu kafukufuku wopangidwa ndi Crolla et al., kusasinthika kwa magwiridwe antchito a analyte pakati pa mizere yopanda kupsinjika ndi kupsinjika kwa reagent kunawunikidwa poyang'ana kubwereza koyamba kwa mayeso aliwonse, ndiyeno kusasinthika kudafaniziridwa ndi kusakhazikika (kuwongolera) Yerekezerani kusasinthasintha. pakati pa zotsatira zomwe zapezedwa) -Koperani 1 ndi Koperani 2.
Mzere woyeserera wa MULTISTIX 10 SG wowerengedwa ndi CLINTEK Status + Analyzer wapangidwa kuti ubwezere mbendera yolakwika m'malo mwa zotsatira zenizeni dongosolo likangozindikira kuti mzere woyeserera ukhoza kukhudzidwa ndi kukhudzidwa kwambiri ndi chinyezi cha chilengedwe.
Mukayesa pa CLINITEK Status + Analyzer, kupitilira 95% (95% nthawi yodalirika: 95.9% mpaka 99.7%) ya mizere yoyeserera ya MULTISTIX 10 SG imabweza mbendera yolakwika, yomwe ikuwonetsa molondola kuti mizere yoyeserera yakhudzidwa ndipo chifukwa chake sichinachitike. zoyenera kugwiritsidwa ntchito (Table 1) .
Table 1. Zolakwika polemba zotsatira za mizere yoyesa yosakanizidwa ndi yoponderezedwa (yowonongeka), yosankhidwa ndi wopanga.
Mgwirizano wapaperesenti pakati pa zobwereza ziwiri zazitsulo zopanda kupsinjika kuchokera kuzinthu zonse za opanga atatu (zolondola ndi ± 1 seti) ndikuchita kwa mizere yopanda kupsinjika (zowongolera).Olembawo adagwiritsa ntchito sikelo ya ± 1 chifukwa uku ndikosiyana kovomerezeka kwa pepala loyesa mkodzo.
Table 2 ndi Table 3 amasonyeza zotsatira zachidule.Pogwiritsa ntchito sikelo yolondola kapena ± 1, palibe kusiyana kwakukulu pakubwereza kubwereza pakati pa zingwe zitatu za opanga popanda kupsinjika (p> 0.05).
Malinga ndi kubwereza mobwerezabwereza kwa mikwingwirima yopanda kupsinjika kwa opanga ena, zidawonedwa kuti kubwereza kawiri kwa mikwingwirima yopanda kupsinjika, pali zitsanzo ziwiri zokha za kusasinthika kwaperesenti.Zitsanzo zimenezi zasonyezedwa.
Kwa magulu a mayeso a Roche ndi diagnostics, dziwani kuchuluka kwa mgwirizano pakati pa kubwereza koyamba kwa bar yopanikizika ndi kubwereza koyamba kwa bar yopanda kupsinjika kuti muwunikire magwiridwe antchito a mzere woyeserera kupsinjika kwa chilengedwe.
Matebulo 4 ndi 5 afotokozera mwachidule zotsatira za analyte aliyense.Chiŵerengero cha mgwirizano wa owerengera awa pansi pazovuta ndizosiyana kwambiri ndi chiwerengero cha mgwirizano wa zochitika zowongolera, ndipo zimalembedwa kuti "zofunika" m'matebulo awa (p<0.05).
Popeza mayeso a nitrate amabweretsanso zotsatira za binary (zoyipa/zabwino), amawonedwa ngati ofuna kuunika pogwiritsa ntchito ±1 seti ya milingo.Ponena za nitrate, poyerekeza ndi kusasinthasintha kwa 96.5% mpaka 98%, mizere yoyesa kupsinjika ya Diagnostic Test Group ndi Roche ili ndi 11.3% mpaka 14.1 yokha pakati pa zotsatira za nitrate zomwe zimapezedwa kubwereza 1 pansi pazikhalidwe zopanda kupsinjika ndikubwereza 1 pansi pazovuta.Mgwirizano wa% udawonedwa pakati pa kubwereza kwa mkhalidwe wosapsinjika (kuwongolera).
Pamayankho a digito kapena osakhala a binary, mayeso a ketone, glucose, urobilinogen, ndi maselo oyera a magazi omwe amachitidwa pa Roche ndi mizere yoyezetsa matenda anali ndi kusiyana kwakukulu pakutulutsa kwa chipika cholondola pakati pa kukakamiza ndi mizere yoyeserera yopanda kupsinjika. .
Pamene mulingo wosasunthika udakulitsidwa ku gulu la ± 1, kuphatikiza mapuloteni (91.5% kusasinthika) ndi maselo oyera amagazi (79.2% kusasinthika), kusiyanasiyana kwa mizere yoyeserera ya Roche kunachepetsedwa kwambiri, ndipo milingo iwiri yokhazikika komanso yopanda kukakamiza (Kusiyanitsa ) Pali mapangano osiyanasiyana.
Pankhani ya mizere yoyesera mu gulu loyesa matenda, kuchuluka kwa urobilinogen (11.3%), maselo oyera a magazi (27.7%), ndi shuga (57.5%) kunapitilirabe kuchepa kwambiri poyerekeza ndi zovuta zawo.
Malingana ndi deta yomwe inapezedwa ndi mzere wa reagent wa Roche ndi Diagnostic Test Group ndi kaphatikizidwe ka analyzer, kusiyana kwakukulu pakati pa zotsatira zosakanizidwa ndi zoponderezedwa kunkawoneka chifukwa cha kukhudzana ndi chinyezi ndi mpweya wa chipinda.Choncho, potengera zotsatira zolakwika kuchokera ku mizere yowonekera, matenda olakwika ndi chithandizo akhoza kuchitika.
Makina ochenjeza odziwikiratu mu Nokia analyzer amalepheretsa kuti zotsatira zake zisafotokozedwe pakapezeka chinyezi.Mu kafukufuku wolamulidwa, wosanthula amatha kuletsa malipoti abodza ndikutulutsa mauthenga olakwika m'malo motulutsa zotsatira.
CLINTEK Status+ analyzer ndi Siemens MULTISTIX 10 SG zoyesa mkodzo zophatikizika ndi ukadaulo wa Auto-Checks zimatha kuzindikira mizere yoyesera yomwe ingakhudzidwe ndi chinyezi chambiri.
The CLINITEK Status+ Analyzer sikuti imangozindikira zingwe zoyeserera za MULTISTIX 10 SG zomwe zimakhudzidwa ndi chinyezi chambiri, komanso imalepheretsa kupereka lipoti la zotsatira zomwe zingakhale zolakwika.
Roche ndi Diagnostic Test Group analyzers alibe njira yodziwira chinyezi.Ngakhale kuti mzere woyesera umakhudzidwa ndi chinyezi chambiri, zida ziwirizi zimafotokoza zotsatira za chitsanzo cha wodwalayo.Zotsatira zomwe zafotokozedwazo zikhoza kukhala zolakwika, chifukwa ngakhale chitsanzo cha odwala omwewo, zotsatira za analyte zidzasiyana pakati pa zowunikira (zosagwedezeka) ndi zowonekera (zopanikizika).
Pakuwunika kosiyanasiyana kwa labotale, Crolla ndi gulu lake adawona kuti nthawi zambiri chipewa cha botolo la mkodzo chimachotsedwa pang'ono kapena kwathunthu.Kuwunikaku kugogomezera kufunikira kwa mabungwe oyesa kuti malingaliro a wopanga payekha athe kukhazikitsidwa mwamphamvu kuti chidebe cha tepicho chitsekeredwe pamene tepiyo sichotsedwa kuti iwunikenso.
M'malo omwe pali ogwiritsira ntchito ambiri (zomwe zimapangitsa kuti kutsata kukhale kovuta kwambiri), ndizothandizanso kugwiritsa ntchito makina odziwitsa woyesa za mizere yomwe yakhudzidwa kuti kuyesako kusachitike.
Amapangidwa kuchokera kuzinthu zomwe zidapangidwa ndi Lawrence Crolla, Cindy Jiménez, ndi Pallavi Patel ochokera ku Northwest Community Hospital ku Arlington Heights, Illinois.
Njira yothetsera vutoli idapangidwa kuti ipereke mayeso achangu, osavuta komanso osavuta kugwiritsa ntchito.Kuchokera kuchipinda chodzidzimutsa kupita ku ofesi ya dokotala, zisankho zoyang'anira zachipatala zitha kupangidwa nthawi yomweyo, motero kuwongolera chitetezo cha odwala, zotsatira zachipatala, komanso kukhutitsidwa kwa odwala onse.
Mfundo zothandizidwa ndi ndalama: Zolemba ndi zofananira zofalitsidwa ndi News-Medical.net zitha kuchokera ku magwero a maubale athu abizinesi omwe alipo, malinga ngati zomwe zili zikuwonjezera phindu ku mzimu waukonzi wa News-Medical.Net, ndiko kuti, maphunziro ndi kudziwitsa webusayiti Alendo omwe ali ndi chidwi ndi kafukufuku wamankhwala, sayansi, zida zamankhwala ndi chithandizo.
Siemens Healthineers Point of Care matenda.(2020, Marichi 13).Kafukufuku woyerekeza wa zowunikira mkodzo zitatu, zomwe zimagwiritsidwa ntchito poyesa kuwunika kwachinyezi kodziwikiratu pamizere yosanthula mkodzo yomwe idawerengedwa ndi chidacho.Nkhani-Zachipatala.Inabwezedwa pa Julayi 13, 2021 kuchokera ku https://www.news-medical.net/whitepaper/20180123/A-Comparative-Study-of-Three-Urinalysis-Analyzers-for-Evaluation-of-Automated-Humidity-Check- -Instrument-Read-Urinalysis-Strips.aspx.
Siemens Healthineers Point of Care matenda."Kafukufuku wofananiza wa osanthula mkodzo atatu omwe amagwiritsidwa ntchito poyesa kuwunika kwachinyezi komwe kumachokera pamzere wowunikira mkodzo powerenga chida".Nkhani-Zachipatala.Julayi 13, 2021. .
Siemens Healthineers Point of Care matenda."Kafukufuku wofananiza wa zowunikira mkodzo zitatu zomwe zimagwiritsidwa ntchito poyesa kuwunika kwachinyezi kwa mzere wosanthula mkodzo powerenga chida".Nkhani-Zachipatala.https://www.news-medical.net/whitepaper/20180123/A-Comparative-Study-of-Three-Urinalysis-Analyzers-for-Evaluation-of-Automated-Humidity-Check-for-Instrument-Read-Urinalysis- Mzere .aspx.(Yafikira pa Julayi 13, 2021).
Siemens Healthineers Point of Care matenda.2020. Kafukufuku woyerekeza wa zowunikira mkodzo zitatu zomwe zimagwiritsidwa ntchito poyesa kuwunika kwa chinyezi chamzere wosanthula mkodzo powerenga chida.News-Medical, idawonedwa pa Julayi 13, 2021, https://www.news-medical.net/whitepaper/20180123/A-Comparative-Study-of-Three-Urinalysis-Analyzers-for-Evaluation-of-Automated- Humidity- Onani -for-Instrument-Read-Urinalysis-Strips.aspx.
Gwiritsani ntchito mayeso a CLINITEST HCG pa CLINITEK analyzer kuti mukwaniritse machitidwe azachipatala komanso miyezo yokhudzika
M'mafunso athu aposachedwa, tidalankhula ndi Dr. Shengjia Zhong za kafukufuku wake waposachedwa, yemwe adafufuza kagwiritsidwe ntchito kakuwongolera malire kuti achepetse kufalikira kwa COVID-19.
M'mafunso awa, News-Medical ndi Pulofesa Emmanuel Stamatakis adakambirana zamavuto azaumoyo okhudzana ndi kusowa tulo.
Chigoba chomwe chimatha kuzindikira COVID-19 chapangidwa.News-Medical idalankhula ndi ofufuza omwe ali kumbuyo kwa lingaliroli kuti aphunzire zambiri momwe limagwirira ntchito.
News-Medical.Net imapereka zidziwitso zachipatalazi molingana ndi izi.Chonde dziwani kuti zambiri zachipatala zomwe zili patsamba lino ndizothandiza m'malo mosintha ubale pakati pa odwala ndi madotolo/madokotala komanso malangizo azachipatala omwe angapereke.
Nthawi yotumiza: Jul-14-2021